Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437523 | 1.00 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11442498 | 1.00 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11446751 | 0.82 | SMN1; SMN2 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11443828 | 0.81 | SMN1; SMN2 (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11450498 | 0.80 | ALDH1A1 (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11436718 | 0.80 | ALDH1A1 (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11506505 | 0.79 | KMT2A (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11506506 | 0.79 | KMT2A (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11507044 | 0.79 | KMT2A (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11450453 | 0.78 | CHRM2 (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | claimed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | claimed |