Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507044 | 1.00 | KMT2A (0.35) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11506505 | 1.00 | KMT2A (0.35) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11479291 | 0.88 | ALDH1A1 (0.38) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11479300 | 0.88 | ALDH1A1 (0.38) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11469344 | 0.88 | ALDH1A1 (0.38) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11517772 | 0.83 | KMT2A (0.34) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11517299 | 0.83 | KMT2A (0.34) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11446751 | 0.82 | SMN1; SMN2 (0.38) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11443828 | 0.81 | SMN1; SMN2 (0.35) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11446487 | 0.81 | TP53 (0.44) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |