Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429873 | 0.84 | MAPT (0.64) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL9624282 | 0.71 | BACE1 (0.41) | MAPTKDM4ECYP3A4ALDH1A1HPGD | |
| SCHEMBL7208168 | 0.69 | ALDH1A1 (0.50) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL29819513 | 0.69 | ALDH1A1 (0.58) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL19255611 | 0.68 | MAPT (0.61) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL774588 | 0.68 | POLB (0.56) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL5888424 | 0.68 | POLB (0.56) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL7211300 | 0.68 | NPC1 (0.66) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL30007636 | 0.67 | NPC1 (0.46) | NPC1MAPTPOLBRAB9AHTT | |
| SCHEMBL1027809 | 0.67 | NPC1 (0.46) | NPC1MAPTPOLBRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199317-A | Printing process | SUBLISTATIC HOLDING SA (CH) | 1980-04-22 | — | — | US | claimed |