Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | GLA | P06280 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 4/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6333668 | 0.87 | ALDH1A1 (0.53) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL28257887 | 0.84 | ALDH1A1 (0.61) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL6494902 | 0.81 | SMN1; SMN2 (0.59) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL6325048 | 0.77 | ALDH1A1 (0.57) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL6439292 | 0.77 | ALDH1A1 (0.60) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL6142611 | 0.75 | ALDH1A1 (0.40) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL11437721 | 0.74 | RPS6KA3 (1.00) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL8033114 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1NPC1MAPTKDM4E | |
| SCHEMBL31198946 | 0.73 | MEN1 (0.57) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL29157472 | 0.72 | SMN1; SMN2 (0.54) | RPS6KA3SMN1; SMN2ALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4144230-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4143033-A | WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |