SCHEMBL6439292

SCHEMBL6439292

Nc1ccc(-c2nc3cccc(N)c3[nH]2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.60
▸ SMN1; SMN2 Q16637 9/20 0.60
▸ HPGD P15428 9/20 0.60
▸ KDM4E B2RXH2 8/20 0.60
▸ MAPT P10636 8/20 0.60
▸ NPC1 O15118 7/20 0.60
▸ RAB9A P51151 6/20 0.60
▸ HSD17B10 Q99714 6/20 0.60
▸ TP53 P04637 5/20 0.60
▸ POLB P06746 4/20 0.60
▸ GFER P55789 3/20 0.60
▸ PARP1 P09874 2/20 0.54
▸ TNKS O95271 1/20 0.54
▸ TNKS2 Q9H2K2 1/20 0.54
▸ MEN1 O00255 8/20 0.51
▸ KMT2A Q03164 8/20 0.51
▸ GAA P10253 6/20 0.51
▸ GLA P06280 5/20 0.51
▸ RECQL P46063 2/20 0.51
▸ RXFP1 Q9HBX9 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1895948 0.88 NPC1 (0.55) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL6325048 0.83 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL21776984 0.83 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL28671805 0.83 NPC1 (0.65) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL28833660 0.82 CHEK2 (0.51) ALDH1A1HPGDKDM4EKMT2A
SCHEMBL7458021 0.80 SMN1; SMN2 (0.53) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL11443276 0.77 RPS6KA3 (0.59) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL6494902 0.77 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL28241148 0.75 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT
SCHEMBL222131 0.75 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577369-B2 High tenacity filled films comprising a polymer having imidazole groups DUPONT SAFETY & CONSTRUCTION, INC. (US) 2026-03-17 — — US claimed
US-20260071385-A1 Papers Having Low Density and High Average Specific Modulus DUPONT SAFETY & CONSTRUCTION INC (US) 2026-03-12 — — US claimed
US-20260049422-A1 Papers Having High Average Specific Modulus and Ultimate Tensile Strength DUPONT SAFETY & CONSTRUCTION INC (US) 2026-02-19 — — US claimed
WO-2025235238-A1 PEEK COMPOSITIONS WITH REDUCED CRYSTALLIZATION RATE DUPONT SAFETY & CONSTRUCTION, INC. (US) 2025-11-13 — — WO claimed
US-20250346755-A1 PEEK Compositions with Reduced Crystallization Rate DUPONT SAFETY & CONTSTRUCTION INC (US) 2025-11-13 — — US claimed
EP-4619457-A1 COMPOSITE COMPOSITION COMPRISING ARAMID COPOLYMER PARTICLES AND A THERMOPLASTIC ENGINEERING POLYMER AND ARTICLES COMPRISING SAME DuPont Safety & Construction, Inc. (US) 2025-09-24 — — EP claimed
EP-4590740-A1 HIGH TENACITY FILLED FILMS COMPRISING A POLYMER HAVING IMIDAZOLE GROUPS DuPont Safety & Construction, Inc. (US) 2025-07-30 — — EP claimed
EP-4590736-A1 HIGH DIELECTRIC CONSTANT NEAT POLYMERIC FILM DuPont Safety & Construction, Inc. (US) 2025-07-30 — — EP claimed
CN-120202242-A High dielectric constant pure polymer film 杜邦安全与建筑公司 2025-06-24 — — CN claimed
CN-120202244-A Composite composition comprising aramid copolymer particles and thermoplastic engineering polymer and article comprising the composition 杜邦安全与建筑公司 2025-06-24 — — CN claimed
CN-112301443-B Three-stage heat setting method of heterocyclic aramid fiber 中蓝晨光化工有限公司 2022-04-12 — — CN claimed
US-11279800-B2 Aramid copolymer yarn having low residual sulfur DUPONT SAFETY & CONSTRUCTION, INC. (US) 2022-03-22 — — US claimed
EP-2802698-A1 SULFUR AND ALKALI METAL CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BOUND HALIDES E. I. Du Pont de Nemours and Company (US) 2014-11-19 — — EP claimed
EP-2802700-A1 ARAMID COPOLYMER YARN HAVING LOW RESIDUAL SULFUR E. I. Du Pont de Nemours and Company (US) 2014-11-19 — — EP claimed
EP-2802697-A1 SULFUR-CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BONDED HALIDES E. I. Du Pont de Nemours and Company (US) 2014-11-19 — — EP claimed
EP-2663587-A1 NEUTRALIZED COPOLYMER CRUMB AND PROCESSES FOR MAKING SAME E.I. Du Pont De Nemours And Company (US) 2013-11-20 — — EP claimed
WO-2013105944-A1 SULFUR AND ALKALI METAL CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BOUND HALIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-07-18 — — WO claimed
WO-2013105940-A1 SULFUR-CONTAINING IMIDAZOLE FIBER HAVING IONICALLY BONDED HALIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-07-18 — — WO claimed
WO-2013105948-A1 ARAMID COPOLYMER YARN HAVING LOW RESIDUAL SULFUR E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-07-18 — — WO claimed
WO-2012097236-A1 NEUTRALIZED COPOLYMER CRUMB AND PROCESSES FOR MAKING SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-19 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049422-A1 Papers Having High Average Specific Modulus and Ultimate Tensile Strength PCNA, PARG, SMCHD1 ALDH1A1 2647/4885SMN1; SMN2 958/4885HPGD 2061/4885
US-12577369-B2 High tenacity filled films comprising a polymer having imidazole groups DDT, DDC, PNMT ALDH1A1 598/4885SMN1; SMN2 2628/4885HPGD 1681/4885
US-20260071385-A1 Papers Having Low Density and High Average Specific Modulus PARN, PARG, PAICS ALDH1A1 1410/4885SMN1; SMN2 1432/4885HPGD 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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