SCHEMBL1144355

SCHEMBL1144355

C=CC(=O)OC(C)C[Si](OCC)(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.40
HPGD P15428 1/20 0.35
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31
THRB P10828 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2718755 0.98 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1132650 0.85 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5605420 0.84 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL21360070 0.82 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1144331 0.81 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28040196 0.81 TSHR (0.34) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL21625001 0.81 TSHR (0.34) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28029121 0.81 TSHR (0.34) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1680182 0.81 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28205294 0.80 FAAH (0.35) TSHRHPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116261491-B Coating agent for plexiglass and plexiglass 株式会社丰田自动织机 2024-07-02 CN claimed
CN-102372887-B Heat-curable resin composition for protective film LG CHEMICAL LTD 2015-01-21 CN claimed
US-20020127330-A1 Organic-inorganic hybrid polymer and method of making same JIN DAN L (US) 2002-09-12 US claimed
US-20010036554-A1 Organic-incorganic hybrid polymer and method of making same NANOFILM LTD 2001-11-01 US claimed
EP-1136520-A2 Organic- inorganic hybrid polymer and method of making the same nanoFILM, Ltd. (US) 2001-09-26 EP claimed
EP-4695332-A1 RUBBER COMPOSITION, AND ASSOCIATED FORMULATION METHOD AND PARTS Airboss of America Corp. (CA) 2026-02-18 EP disclosed
EP-4581064-A1 PREPARATION OF SILANE-GRAFTED EPDM AND MOISTURE CURING THEREOF Airboss of America Corp. (CA) 2025-07-09 EP disclosed
WO-2024214043-A1 RUBBER COMPOSITION, AND ASSOCIATED FORMULATION METHOD AND PARTS AIRBOSS OF AMERICA CORP. (CA) 2024-10-17 WO disclosed
EP-4386246-A2 LOW SPEED CROSS-LINKING CATALYST FOR SILANE-GRAFTED PLASTOMERS Borealis AG (AT) 2024-06-19 EP disclosed
US-11981781-B2 High speed cross-linking of grafted plastomers BOREALIS AG (AT) 2024-05-14 US disclosed
CN-113614120-B High-speed crosslinking of grafted plastomers 博里利斯股份公司 2024-03-22 CN disclosed
WO-2024047583-A1 PREPARATION OF SILANE-GRAFTED EPDM AND MOISTURE CURING THEREOF AIRBOSS OF AMERICA CORP. (CA) 2024-03-07 WO disclosed
US-20040022706-A1 Paint composition, proces for producing wear-resistant coating film using the same ,and wear-resistant coating film comprising the same KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2004-02-05 US disclosed
US-6607590-B2 Clear protective thin film NANOFILM, LTD. 2003-08-19 US disclosed
US-6451420-B1 ORGANIC POLYMER AND SILICA MOLECULES CHEMICALLY BONDED TOGETHER BY COVALENT BONDS, POLYMERIZED PRODUCT OF OLIGOMERS FROM HYDROLYSIS OF TETRAALKYL SILICATE, EPOXYALKYLALKOXY SILANES, ACRYLOXYALKYLALKOXY;LENSES NANOFILM, LTD. 2002-09-17 US disclosed
US-20020127330-A1 Organic-inorganic hybrid polymer and method of making same JIN DAN L (US) 2002-09-12 US disclosed
US-20010036554-A1 Organic-incorganic hybrid polymer and method of making same NANOFILM LTD 2001-11-01 US disclosed
EP-1136520-A2 Organic- inorganic hybrid polymer and method of making the same nanoFILM, Ltd. (US) 2001-09-26 EP disclosed
US-5795690-A MULTILAYER; ELECTROCONDUCTIVITY SUBSTRATE, CROSSLINKED UNDERCOATINGS AND PHOTOSENSITIVITY FUJI XEROX CO., LTD. (JP) 1998-08-18 US disclosed
EP-0785477-A2 Electrophotographic photoreceptor, image forming apparatus and image forming process FUJI XEROX CO., LTD. (JP) 1997-07-23 EP disclosed