Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118750 | 0.72 | MAOB (0.47) | MAPK14PDE5AMAOBGAA | |
| SCHEMBL6559983 | 0.70 | MAOB (0.43) | MAPTKDM4EALDH1A1POLBPDE5A | |
| SCHEMBL6559981 | 0.69 | PDE5A (0.48) | MAPTKDM4EALDH1A1POLBPDE5A | |
| SCHEMBL27656755 | 0.69 | KDM4E (0.46) | MAPK14MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6561528 | 0.68 | KDM4E (0.49) | MAPTKDM4EALDH1A1POLBPDE5A | |
| SCHEMBL10972035 | 0.68 | PDE5A (0.52) | MAPTKDM4EALDH1A1POLBPDE5A | |
| SCHEMBL7041646 | 0.68 | PPARA (0.53) | — | |
| SCHEMBL10975462 | 0.67 | PDE5A (0.51) | MAPTKDM4EALDH1A1POLBPDE5A | |
| SCHEMBL7038827 | 0.67 | PPARA (0.46) | — | |
| SCHEMBL8474968 | 0.66 | HTR1A (0.46) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017332-A1 | Pharmaceutical heterocyclic compounds, processes for their preparation and compositions containing them | FISONS plc (GB) | 1980-10-15 | — | — | EP | disclosed |