Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CBX7 | O95931 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444026 | 0.92 | TIMP3 (0.46) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11587244 | 0.92 | TIMP3 (0.46) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11444114 | 0.89 | TIMP3 (0.46) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11444111 | 0.88 | TIMP3 (0.45) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11587242 | 0.88 | P2RY11 (0.53) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL10413972 | 0.85 | TIMP3 (0.58) | KMT2AMEN1MAPTTIMP3TDP1 | |
| SCHEMBL11136276 | 0.84 | APEX1 (0.55) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11588104 | 0.83 | TIMP3 (0.59) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11433049 | 0.83 | TIMP3 (0.59) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL10413406 | 0.82 | MEN1 (0.58) | KMT2AMEN1POLBMAPTTIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |