Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 4/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CD40 | P25942 | 2/20 | 0.43 |
| ▸ | CD40LG | P29965 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444114 | 0.99 | TIMP3 (0.46) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL11432549 | 0.91 | TIMP3 (0.55) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL11429449 | 0.91 | TIMP3 (0.55) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL11444026 | 0.90 | TIMP3 (0.46) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL11587244 | 0.90 | TIMP3 (0.46) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL11444025 | 0.88 | KMT2A (0.46) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL11437640 | 0.88 | CD40 (0.50) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL10413972 | 0.87 | TIMP3 (0.58) | TIMP3KMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL11437646 | 0.86 | CD40 (0.51) | TIMP3KCNMA1KMT2AMEN1TDP1 | |
| SCHEMBL11420299 | 0.86 | TIMP3 (0.58) | TIMP3KMT2AMEN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |