Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CD40 | P25942 | 2/20 | 0.39 |
| ▸ | CD40LG | P29965 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444085 | 0.99 | ALDH1A1 (0.40) | ALDH1A1CASP6CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL11437677 | 0.93 | CASP6 (0.44) | ALDH1A1CASP6CYP2C9CYP2C19RORC | |
| SCHEMBL11437668 | 0.92 | CASP6 (0.43) | ALDH1A1CASP6RORCMAPTRAB9A | |
| SCHEMBL11433142 | 0.87 | APEX1 (0.56) | ALDH1A1CYP2C9CYP2C19RORCMAPT | |
| SCHEMBL11440007 | 0.87 | APEX1 (0.44) | ALDH1A1CYP2C9CYP2C19RORCMAPT | |
| SCHEMBL11418896 | 0.87 | APEX1 (0.44) | ALDH1A1CYP2C9CYP2C19RORCMAPT | |
| SCHEMBL11152668 | 0.87 | APEX1 (0.44) | ALDH1A1CYP2C9CYP2C19RORCMAPT | |
| SCHEMBL11433134 | 0.86 | APEX1 (0.55) | ALDH1A1CYP2C9CYP2C19RORCMAPT | |
| SCHEMBL11418887 | 0.86 | APEX1 (0.43) | ALDH1A1CYP2C9CYP2C19RORCMAPT | |
| SCHEMBL11444087 | 0.85 | APEX1 (0.43) | ALDH1A1CYP2C9CYP2C19HSD17B10RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |