Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240555 | 0.87 | AKR1C3 (0.42) | MAPTKDM4ENPC1ALDH1A1AKR1C3 | |
| SCHEMBL11774717 | 0.86 | LMNA (0.42) | NR4A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL11725662 | 0.85 | NR4A1 (0.47) | NR4A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL11445975 | 0.85 | NR4A1 (0.51) | NR4A1LMNAMAPTKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL11725673 | 0.83 | ABCB11 (0.50) | NR4A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL11772462 | 0.83 | NR4A1 (0.46) | NR4A1LMNAKDM4ENPC1ALDH1A1 | |
| SCHEMBL11774200 | 0.82 | POLB (0.41) | NR4A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL11772647 | 0.82 | ELANE (0.43) | NR4A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL11445302 | 0.81 | NR4A1 (0.37) | NR4A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL11725138 | 0.78 | NR4A1 (0.46) | NR4A1LMNAMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4192890-A | Novel benzoylphenylacetic acid esters | ROUSSEL UCLAF (FR) | 1980-03-11 | — | — | US | disclosed |
| US-4147790-A | (4-Phenyl-piperazino alkyl)-3-benzoyl-benzene alkanoates | ROUSSEL UCLAF (FR) | 1979-04-03 | — | — | US | disclosed |