Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PDE1A | P54750 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PRLHR | P49683 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453418 | 0.73 | PDE1A (0.41) | ABCB1LMNACYP3A4TSHRNR1I2 | |
| SCHEMBL9529005 | 0.73 | ABCG2 (0.45) | ABCB1ABCG2LMNACYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL10491435 | 0.72 | ABCG2 (0.45) | ABCB1ABCG2LMNACYP3A4TSHR | |
| SCHEMBL11174540 | 0.71 | TP53 (0.39) | ABCB1ABCG2LMNACYP3A4TSHR | |
| SCHEMBL9532750 | 0.71 | CYP3A4 (0.46) | LMNACYP3A4TSHRNR1I2CYP1A2 | |
| SCHEMBL10491433 | 0.71 | CYP3A4 (0.46) | LMNACYP3A4TSHRNR1I2CYP1A2 | |
| SCHEMBL10834796 | 0.70 | CYP3A4 (0.45) | ABCB1ABCG2LMNACYP3A4TSHR | |
| SCHEMBL11445161 | 0.70 | ABCG2 (0.52) | ABCB1ABCG2LMNACYP3A4TSHR | |
| SCHEMBL11982876 | 0.69 | CYP3A4 (0.49) | LMNACYP3A4TSHRNR1I2CYP1A2 | |
| SCHEMBL9318482 | 0.69 | CYP3A4 (0.49) | LMNACYP3A4TSHRNR1I2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | disclosed |