Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445075 | 0.79 | MEN1 (0.37) | CYP3A4LMNACYP2D6NR1I2CYP1A2 | |
| SCHEMBL9532750 | 0.74 | CYP3A4 (0.46) | PDE1APDE1BPDE1CCYP3A4LMNA | |
| SCHEMBL10491433 | 0.74 | CYP3A4 (0.46) | PDE1APDE1BPDE1CCYP3A4LMNA | |
| SCHEMBL11445109 | 0.73 | ABCB1 (0.44) | PDE1APDE1BPDE1CCYP3A4LMNA | |
| SCHEMBL11473408 | 0.73 | PDE1A (0.47) | PDE1APDE1BPDE1CCYP3A4LMNA | |
| SCHEMBL11471795 | 0.72 | CYP3A4 (0.46) | PDE1ACYP3A4LMNACYP2D6NR1I2 | |
| SCHEMBL11445096 | 0.71 | CYP3A4 (0.45) | PDE1APDE1BPDE1CCYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL11485438 | 0.71 | CYP3A4 (0.45) | PDE1ACYP3A4LMNACYP2D6NR1I2 | |
| SCHEMBL10491371 | 0.69 | CYP3A4 (0.44) | PDE1APDE1BPDE1CCYP3A4LMNA | |
| SCHEMBL10834796 | 0.68 | CYP3A4 (0.45) | PDE1APDE1BPDE1CCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | disclosed |