SCHEMBL11445127

SCHEMBL11445127

O=C(O)OC(O)C(Cl)(Cl)Cl.[CaH2]

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4594504 0.74 LMNA (0.33) LMNATSHRCYP2C19
SCHEMBL6419921 0.74 HTT (0.34) LMNAALDH1A1TP53TSHRCYP2C19
SCHEMBL30399652 0.70 HTT (0.32)
SCHEMBL2294883 0.70 ALDH1A1 (0.33) LMNAALDH1A1TP53TSHR
SCHEMBL575137 0.69 LMNA (0.34) LMNACYP2C19
Hydrochloric Acid SCHEMBL11629040 0.68 LMNA (0.32) LMNAALDH1A1TP53TSHR
SCHEMBL9474123 0.68 ALDH1A1 (0.36) ALDH1A1TP53TSHR
SCHEMBL10464120 0.67
SCHEMBL14762936 0.67 TSHR (0.31) ALDH1A1TP53TSHR
SCHEMBL3153977 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4194920-A EMULSION POLYMERIZATION TO ENCAPSULATE MICRONIZED PIGMENTS Darrah, Marion (US) 1980-03-25 US disclosed
US-4154621-A Intrachromoleucospheruloid pigment compositions and processes for producing the same Darrah, Marion (US) 1979-05-15 US disclosed