Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.55 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.48 |
| ▸ | CHRNG | P07510 | 1/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | CHRND | Q07001 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599644 | 0.85 | KMT2A (0.55) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL31701871 | 0.85 | HTR2C (0.51) | HTR2CHTR2ABRPF1SLC6A2SLC6A4 | |
| SCHEMBL16292956 | 0.80 | HTR2C (0.51) | HTR2CBRPF1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2707057 | 0.77 | HTR2C (0.63) | HTR2CKMT2AMEN1ALDH1A1HTR2A | |
| SCHEMBL21484828 | 0.77 | MEN1 (0.49) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL22542016 | 0.77 | SLC6A2 (0.63) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10186122 | 0.77 | CA12 (0.61) | KMT2AMEN1LMNAPDE4D | |
| SCHEMBL16951870 | 0.77 | HTR2C (0.41) | HTR2CKMT2AMEN1ALDH1A1HTR2A | |
| SCHEMBL23712339 | 0.76 | HTR2C (0.61) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5669793 | 0.76 | HTR2C (0.61) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188396-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |