Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453396 | 1.00 | BLM (0.48) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL6271680 | 0.91 | BLM (0.56) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL811625 | 0.83 | BLM (0.48) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL114059 | 0.79 | LMNA (0.63) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL3995713 | 0.79 | LMNA (0.63) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL26109378 | 0.78 | BLM (0.56) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL11363905 | 0.77 | LMNA (0.68) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL9466533 | 0.77 | LMNA (0.68) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL11359162 | 0.77 | LMNA (0.68) | BLMLMNAPTPN1MEN1CYP3A4 | |
| SCHEMBL9756758 | 0.77 | LMNA (0.68) | BLMLMNAPTPN1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191842-A | Protected alcohols | HOFFMANN-LA ROCHE INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4182776-A | Method of treating lipidemia with aryloxyalkylaminobenzoic acids and esters | AMERICAN CYANAMID COMPANY (US) | 1980-01-08 | — | — | US | disclosed |
| US-4151205-A | Synthesis of vitamin E | HOFFMAN-LA ROCHE INC. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4051153-A | Intermediates in the synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1977-09-27 | — | — | US | disclosed |