Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440302 | 0.95 | HRH3 (0.53) | KCNH2HRH3SIGMAR1BCL2L1AOC3 | |
| SCHEMBL2277966 | 0.89 | SIGMAR1 (0.62) | KCNH2HRH3SIGMAR1BCL2L1AOC3 | |
| SCHEMBL11497165 | 0.84 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL554550 | 0.84 | AOC3 (0.59) | KCNH2HRH3SIGMAR1BCL2L1AOC3 | |
| SCHEMBL27629480 | 0.81 | KCNH2 (0.58) | KCNH2HRH3ALDH1A1IGF1RALOX15 | |
| SCHEMBL9671267 | 0.80 | SIGMAR1 (0.75) | KCNH2HRH3SIGMAR1ALDH1A1TSHR | |
| SCHEMBL11131252 | 0.79 | AOC3 (0.59) | KCNH2HRH3SIGMAR1AOC3L3MBTL1 | |
| SCHEMBL9670726 | 0.78 | SIGMAR1 (0.79) | KCNH2HRH3SIGMAR1ALDH1A1TSHR | |
| SCHEMBL9670507 | 0.78 | SIGMAR1 (0.79) | KCNH2HRH3SIGMAR1ALDH1A1TSHR | |
| SCHEMBL5545290 | 0.77 | IGF1R (0.49) | KCNH2IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |