Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446123 | 0.95 | KCNH2 (0.51) | HRH3BCL2L1AOC3L3MBTL1ALDH1A1 | |
| SCHEMBL554550 | 0.89 | AOC3 (0.59) | HRH3BCL2L1AOC3L3MBTL1TSHR | |
| SCHEMBL2277966 | 0.83 | SIGMAR1 (0.62) | HRH3BCL2L1AOC3L3MBTL1TSHR | |
| SCHEMBL11387795 | 0.79 | BCL2L1 (0.50) | BCL2L1AOC3L3MBTL1TSHRKCNH2 | |
| SCHEMBL11497165 | 0.79 | KCNH2 (0.68) | KCNH2AGER | |
| SCHEMBL9670561 | 0.79 | SIGMAR1 (0.64) | HRH3AOC3KCNH2SIGMAR1SLC6A2 | |
| SCHEMBL27629480 | 0.79 | KCNH2 (0.58) | HRH3ALDH1A1KCNH2SLC6A2HTR2A | |
| SCHEMBL12418966 | 0.79 | PPARA (0.45) | L3MBTL1ALDH1A1 | |
| SCHEMBL11458154 | 0.78 | AOC3 (0.61) | HRH3AOC3ALDH1A1KCNH2SIGMAR1 | |
| SCHEMBL14528082 | 0.77 | FDPS (0.62) | BCL2L1AOC3KCNH2SIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |