Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127342 | 0.82 | PTK2 (0.49) | PTK2L3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL5460719 | 0.82 | MAPT (0.52) | L3MBTL1TDP1NPC1RAB9AKMT2A | |
| SCHEMBL12515442 | 0.82 | PTK2 (0.49) | PTK2L3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL9995068 | 0.82 | PTK2 (0.49) | PTK2L3MBTL1TDP1NPC1KMT2A | |
| SCHEMBL9198708 | 0.82 | ALDH1A1 (0.44) | PTK2L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL3934451 | 0.82 | ALDH1A1 (0.44) | PTK2L3MBTL1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL10388715 | 0.81 | ALDH1A1 (0.43) | PTK2L3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL9648858 | 0.81 | ALDH1A1 (0.43) | PTK2L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL9646590 | 0.80 | ALDH1A1 (0.46) | PTK2L3MBTL1TDP1KMT2AMAPT | |
| SCHEMBL9646715 | 0.80 | ALDH1A1 (0.46) | PTK2L3MBTL1TDP1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4203988-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-05-20 | — | — | US | disclosed |