Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446728 | 0.90 | ALDH1A1 (0.40) | TP53OPRM1PTGDR2SIGMAR1KMT2A | |
| SCHEMBL11447348 | 0.90 | ALDH1A1 (0.40) | TP53OPRM1PTGDR2SIGMAR1KMT2A | |
| SCHEMBL11550110 | 0.89 | MEN1 (0.41) | TP53OPRM1TSHRCYP3A4MAPT | |
| SCHEMBL11434896 | 0.84 | TP53 (0.47) | TP53OPRM1TSHRCYP3A4MAPT | |
| SCHEMBL11446523 | 0.84 | TP53 (0.47) | TP53OPRM1TSHRCYP3A4MAPT | |
| SCHEMBL11447041 | 0.83 | TP53 (0.46) | TP53OPRM1TSHRCYP3A4MAPT | |
| SCHEMBL11506506 | 0.81 | KMT2A (0.35) | OPRM1MAPTPTGDR2SIGMAR1KMT2A | |
| SCHEMBL11506505 | 0.81 | KMT2A (0.35) | OPRM1MAPTPTGDR2SIGMAR1KMT2A | |
| SCHEMBL11507044 | 0.81 | KMT2A (0.35) | OPRM1MAPTPTGDR2SIGMAR1KMT2A | |
| SCHEMBL11456609 | 0.80 | ALDH1A1 (0.39) | TP53OPRM1PTGDR2SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |