Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11447042 | 0.91 | MEN1 (0.39) | MEN1KMT2ASIGMAR1TSHRCNR2 | |
| SCHEMBL11446891 | 0.89 | MEN1 (0.40) | MEN1KMT2ATSHRCNR2NPC1 | |
| SCHEMBL11446841 | 0.89 | SIGMAR1 (0.40) | MEN1KMT2ASIGMAR1CNR2NPC1 | |
| SCHEMBL11447020 | 0.89 | OPRD1 (0.42) | MEN1KMT2ASIGMAR1CNR2NPC1 | |
| SCHEMBL11434897 | 0.88 | MEN1 (0.39) | MEN1KMT2ASIGMAR1TSHRCNR2 | |
| SCHEMBL11446647 | 0.88 | TP53 (0.48) | MEN1KMT2ASIGMAR1NPC1KDM4E | |
| SCHEMBL11334030 | 0.87 | CNR2 (0.44) | MEN1KMT2ASIGMAR1TSHRCNR2 | |
| SCHEMBL11334034 | 0.85 | MEN1 (0.39) | MEN1KMT2ATSHRCNR2NPC1 | |
| SCHEMBL11332175 | 0.85 | SIGMAR1 (0.42) | MEN1KMT2ASIGMAR1CNR2NPC1 | |
| SCHEMBL11347007 | 0.85 | SIGMAR1 (0.43) | MEN1KMT2ASIGMAR1CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | claimed |
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |