SCHEMBL6550304

SCHEMBL6550304

CCCCCCCCCCCCCCCCCCN1C(=O)C2(CCCCC2)NC2(CCCCC2)C1=O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.43
PTGS2 P35354 3/20 0.43
MGLL Q99685 2/20 0.43
FAAH O00519 2/20 0.43
TACR1 P25103 1/20 0.40
CNR1 P21554 1/20 0.40
ALOX5 P09917 2/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
CYP19A1 P11511 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11446008 1.00 PTGS1 (0.43) PTGS1PTGS2MGLLFAAHTACR1
SCHEMBL11445776 0.92 POLB (0.45) POLBKMT2ALMNA
SCHEMBL11445913 0.92 POLB (0.45) POLBKMT2ALMNA
SCHEMBL11464878 0.90 POLB (0.46) POLBKMT2ALMNA
SCHEMBL11822676 0.80 ALOX5 (0.37) PTGS1PTGS2MGLLFAAHTACR1
SCHEMBL11823011 0.80 ALOX5 (0.37) PTGS1PTGS2MGLLFAAHTACR1
SCHEMBL5605674 0.80 TACR1 (0.46) PTGS1PTGS2MGLLTACR1CNR1
SCHEMBL6017344 0.78 TACR1 (0.47) PTGS1PTGS2MGLLFAAHTACR1
SCHEMBL11445775 0.77 SLC6A4 (0.33) ALOX5POLBKMT2A
SCHEMBL7517452 0.76 PTGS1 (0.42) PTGS1PTGS2MGLLFAAHCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP claimed
US-6562084-B2 Against discoloration and fading; also a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US claimed
US-20030051392-A1 CANDLE WAX STABILIZED WITH PIPERAZINDIONES CIBA SPECIALTY CHEMICALS CORP. 2003-03-20 US claimed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO claimed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US claimed
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
US-6562084-B2 Against discoloration and fading; also a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US disclosed
US-20030051392-A1 CANDLE WAX STABILIZED WITH PIPERAZINDIONES CIBA SPECIALTY CHEMICALS CORP. 2003-03-20 US disclosed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4007157-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed