Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454835 | 0.92 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL11446758 | 0.89 | ADRA1D (0.47) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL11456867 | 0.89 | KMT2A (0.50) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL11446663 | 0.88 | GFER (0.50) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL11465437 | 0.86 | ADRA1D (0.52) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL11454591 | 0.85 | GAA (0.48) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL11446599 | 0.84 | ADRA1D (0.51) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11457400 | 0.83 | ADRA1D (0.53) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL11446215 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL11447378 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4085107-A | ANALGESICS | PENNWALT CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |