Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466715 | 0.96 | CHRNB4 (0.45) | CHRNB4CHRNA3GHSRLTA4H | |
| SCHEMBL11448286 | 0.84 | CHRNB4 (0.46) | CHRNB4CHRNA3 | |
| SCHEMBL11447738 | 0.84 | LTA4H (0.45) | CHRNA3LTA4H | |
| SCHEMBL11455927 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3GHSR | |
| SCHEMBL11455784 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3GHSR | |
| SCHEMBL11712027 | 0.82 | CHRNB4 (0.44) | CHRNB4CHRNA3 | |
| SCHEMBL14578215 | 0.81 | CHRNB4 (0.52) | CHRNB4CHRNA3LTA4H | |
| SCHEMBL11448940 | 0.81 | CHRNB4 (0.43) | CHRNB4CHRNA3DRD3LTA4H | |
| SCHEMBL7955171 | 0.80 | CHRNB4 (0.52) | CHRNB4CHRNA3LTA4H | |
| SCHEMBL11450540 | 0.80 | CHRNB4 (0.52) | CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |