Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448940 | 0.96 | CHRNB4 (0.43) | CHRNB4CHRNA3 | |
| SCHEMBL11448956 | 0.85 | PTPRZ1 (0.46) | CHRNA3 | |
| SCHEMBL11447441 | 0.84 | CHRNB4 (0.49) | CHRNB4CHRNA3 | |
| SCHEMBL11458068 | 0.81 | LTA4H (0.49) | — | |
| SCHEMBL11466710 | 0.81 | HRH3 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11466715 | 0.81 | CHRNB4 (0.45) | CHRNB4CHRNA3 | |
| SCHEMBL11458473 | 0.80 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11712027 | 0.79 | CHRNB4 (0.44) | CHRNB4CHRNA3 | |
| SCHEMBL11447774 | 0.78 | LTA4H (0.51) | CHRNB4CHRNA3 | |
| SCHEMBL14578215 | 0.78 | CHRNB4 (0.52) | CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |