Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448101 | 0.87 | ALDH1A1 (0.54) | ALDH1A1ESRRAMAPK14NR1H4ATM | |
| SCHEMBL11456067 | 0.77 | ALDH1A1 (0.56) | ALDH1A1NR1H4L3MBTL1HPGDKDM4E | |
| SCHEMBL28030787 | 0.75 | ALDH1A1 (0.67) | ALDH1A1ATMGAAHPGDKDM4E | |
| SCHEMBL10321409 | 0.72 | ALDH1A1 (0.72) | ALDH1A1ESRRAGAAHPGDKDM4E | |
| SCHEMBL11244625 | 0.70 | ALDH1A1 (0.60) | ALDH1A1GAAHPGDKDM4ECA2 | |
| SCHEMBL11450751 | 0.69 | ALDH1A1 (0.50) | ALDH1A1GAAL3MBTL1HPGDKDM4E | |
| SCHEMBL21753923 | 0.68 | ALDH1A1 (0.67) | ALDH1A1ATMGAANPSR1L3MBTL1 | |
| SCHEMBL769384 | 0.68 | ALDH1A1 (0.55) | ALDH1A1GAAHPGDKDM4EMAPT | |
| SCHEMBL221405 | 0.68 | ALDH1A1 (0.51) | ALDH1A1ATMGAAXBP1NPSR1 | |
| SCHEMBL12813690 | 0.68 | ALDH1A1 (0.49) | ALDH1A1GAAHPGDKDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222767-A | Certain herbicidal sulfonates and sulfamates | FISONS LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| US-4162154-A | BENZOFURAN DERIVATIVES | FISONS LIMITED (GB) | 1979-07-24 | — | — | US | disclosed |