SCHEMBL221405

SCHEMBL221405

COc1ccc(O)c(C(C)(C)CC(C)(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
GAA P10253 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
MCL1 Q07820 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
ERN1 O75460 1/20 0.42
ESR1 P03372 1/20 0.40
CYP19A1 P11511 1/20 0.40
ESR2 Q92731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18944155 0.84 ALDH1A1 (0.53) ALDH1A1GAASMN1; SMN2KDM4EMEN1
SCHEMBL11799605 0.83 ALDH1A1 (0.43) ALDH1A1GAASMN1; SMN2KDM4EMEN1
SCHEMBL12405380 0.83 ALDH1A1 (0.51) ALDH1A1GAASMN1; SMN2KDM4EMEN1
SCHEMBL11786492 0.81 GAA (0.50) ALDH1A1GAASMN1; SMN2KDM4EMEN1
SCHEMBL221406 0.81 CNR2 (0.53) ALDH1A1GAASMN1; SMN2KDM4EMEN1
SCHEMBL77848 0.81 CYP3A4 (0.60) ALDH1A1GAASMN1; SMN2RECQLMCL1
Methoxymethane SCHEMBL9554769 0.81 ALDH1A1 (0.55) ALDH1A1GAASMN1; SMN2MEN1MAPT
SCHEMBL5079358 0.80 CA2 (0.62) ALDH1A1GAASMN1; SMN2MAPTCA1
SCHEMBL6142004 0.80 ALDH1A1 (0.73) ALDH1A1GAASMN1; SMN2KDM4EMEN1
SCHEMBL35535 0.80 ALDH1A1 (0.73) ALDH1A1GAASMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029150-B2 Golf ball having medium positive gradient quotient and low trans content ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-7410429-B1 Negative hardness gradient inner core for dual core golf ball ACUSHNET COMPANY (US) 2008-08-12 US disclosed
US-20080153629-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-26 US disclosed
US-20080146380-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-19 US disclosed
US-20080146378-A1 Thick Inner Cover Multi-layer Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-06-19 US disclosed
US-4631252-A PHOTOGRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1986-12-23 US disclosed
US-4616082-A PHOTOGRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1986-10-07 US disclosed
US-4549015-A PHOTOHRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1985-10-22 US disclosed
EP-0098241-B1 HYDROQUINONE ETHERS AND A PROCESS FOR PREPARING THEM CIBA-GEIGY AG (CH) 1985-10-02 EP disclosed
EP-0098241-A1 Hydroquinone ethers and a process for preparing them CIBA-GEIGY AG (CH) 1984-01-11 EP disclosed
US-3984940-A Degradable plastic REICH MURRAY 1976-10-12 US disclosed