Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 7/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.44 |
| ▸ | ESRRB | O95718 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450110 | 0.97 | SLC2A1 (0.44) | SLC2A1HRH3ESRRGESR1PTPRZ1 | |
| SCHEMBL11447817 | 0.86 | CHRNB4 (0.49) | HRH3 | |
| SCHEMBL11449491 | 0.84 | CHRNB4 (0.47) | HRH3 | |
| SCHEMBL11449200 | 0.84 | SLC2A1 (0.49) | SLC2A1HRH3ESRRGESR1ESRRB | |
| SCHEMBL11457965 | 0.83 | CHRNB1 (0.55) | SLC2A1HRH3KCNH2 | |
| SCHEMBL11459556 | 0.82 | PIM1 (0.47) | SLC2A1HRH3ESRRGESR1ESRRB | |
| SCHEMBL11455761 | 0.82 | SLC2A1 (0.47) | SLC2A1HRH3ESRRGESR1ESRRB | |
| SCHEMBL11448234 | 0.81 | CHRNB1 (0.52) | SLC2A1HRH3ESRRGESR1 | |
| SCHEMBL14577979 | 0.81 | SLC2A1 (0.53) | SLC2A1HRH3ESRRGESR1ESRRB | |
| SCHEMBL11449436 | 0.81 | LTA4H (0.54) | SLC2A1HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |