Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317304 | 0.86 | HTT (0.45) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11361092 | 0.81 | PKM (0.43) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11448645 | 0.81 | SMN1; SMN2 (0.45) | HTTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL11315249 | 0.79 | HTT (0.47) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11363854 | 0.77 | PKM (0.58) | HTTPKMSMN1; SMN2RAB9ATSHR | |
| SCHEMBL11361085 | 0.76 | HRH4 (0.44) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11361088 | 0.76 | HRH4 (0.44) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11358702 | 0.75 | SMN1; SMN2 (0.53) | HTTPKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30648520 | 0.74 | NPC1 (0.55) | HTTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL569633 | 0.74 | NPC1 (0.55) | HTTSMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228291-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-14 | — | — | US | disclosed |