Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 10/20 | 0.56 |
| ▸ | FABP2 | P12104 | 2/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458497 | 0.87 | PPARA (0.67) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11448560 | 0.86 | PPARA (0.65) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11449011 | 0.85 | PPARA (0.66) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11569812 | 0.82 | PPARA (0.62) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3811479 | 0.80 | PPARA (0.81) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| Clofibric Acid SCHEMBL102826 | 0.79 | PPARA (1.00) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| Clofibric Acid SCHEMBL2227936 | 0.79 | PPARA (1.00) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11460968 | 0.78 | PPARA (0.56) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| Clofibric Acid SCHEMBL10634899 | 0.78 | PPARA (0.96) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| Clofibric Acid SCHEMBL11798234 | 0.78 | PPARA (0.96) | PPARAMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4214094-A | ANTILIPEMIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |