Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449478 | 1.00 | HSD17B10 (0.47) | HSD17B10PPARGNFE2L2LMNASLC9A1 | |
| SCHEMBL11449419 | 0.80 | TSHR (0.46) | SLC9A1TSHRNPSR1RXFP1SIRT2 | |
| SCHEMBL6273531 | 0.77 | TSHR (0.53) | SLC9A1TSHRNPSR1RXFP1SIRT2 | |
| SCHEMBL2803342 | 0.75 | SLC9A1 (0.55) | SLC9A1TSHRNPSR1RXFP1F2 | |
| SCHEMBL958454 | 0.74 | TSHR (0.50) | SLC9A1TSHRNPSR1RXFP1GAA | |
| SCHEMBL11449443 | 0.71 | TSHR (0.48) | HSD17B10LMNASLC9A1TSHRNPSR1 | |
| SCHEMBL5186016 | 0.71 | TSHR (0.46) | SLC9A1TSHRNPSR1RXFP1SIRT2 | |
| SCHEMBL278207 | 0.69 | PPARG (0.56) | PPARGNFE2L2LMNATSHRNPSR1 | |
| SCHEMBL640172 | 0.69 | TSHR (0.54) | SLC9A1TSHRNPSR1RXFP1SIRT2 | |
| SCHEMBL7198576 | 0.69 | TSHR (0.48) | LMNASLC9A1TSHRNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242507-A | Sulfonic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-30 | — | — | US | disclosed |