Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452400 | 0.89 | FFAR1 (0.49) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL11451494 | 0.88 | CYP11B1 (0.45) | PPARGPPARAL3MBTL1MAPTMEN1 | |
| SCHEMBL11450230 | 0.85 | MAPT (0.51) | PPARGPPARAL3MBTL1MAPTMEN1 | |
| SCHEMBL11451159 | 0.79 | MEN1 (0.48) | PPARGPPARAL3MBTL1MEN1KMT2A | |
| SCHEMBL10964710 | 0.77 | EPHX2 (0.62) | PPARGPPARAL3MBTL1EPHX2MAPT | |
| SCHEMBL4637996 | 0.77 | NPC1 (0.56) | MAPTMEN1KMT2ALMNA | |
| SCHEMBL163796 | 0.76 | CYP1A2 (0.50) | PPARGPPARAL3MBTL1EPHX2MAPT | |
| SCHEMBL11450033 | 0.75 | PPARG (0.47) | PPARGPPARAL3MBTL1MAPTKMT2A | |
| SCHEMBL10968135 | 0.75 | L3MBTL1 (0.50) | PPARGPPARAL3MBTL1EPHX2MAPT | |
| SCHEMBL11646451 | 0.75 | PPARA (0.53) | PPARGPPARAMAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019796-A1 | Propionic acid esters, preparation of these compounds, herbicides containing these compounds as active substances, and the use of such compounds and agents for combating weeds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-12-10 | — | — | EP | claimed |
| EP-0019796-A1 | Propionic acid esters, preparation of these compounds, herbicides containing these compounds as active substances, and the use of such compounds and agents for combating weeds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-12-10 | — | — | EP | disclosed |