Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513339 | 0.78 | TDP1 (0.46) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL10455911 | 0.78 | TDP1 (0.44) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL11458864 | 0.76 | TDP1 (0.43) | TDP1L3MBTL1POLBTHRBRECQL | |
| Alcohol SCHEMBL10456917 | 0.75 | TDP1 (0.42) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL10875973 | 0.75 | TDP1 (0.42) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL11106587 | 0.74 | TDP1 (0.44) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL10705437 | 0.74 | TDP1 (0.41) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL21340375 | 0.74 | TDP1 (0.41) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL10705319 | 0.73 | TDP1 (0.43) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL19469555 | 0.73 | TSHR (0.50) | TDP1L3MBTL1TSHRSMN1; SMN2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4237158-A | FOR PLANT DISEASES; PLANT GROWTH REGULATORS | ROHM AND HAAS COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4118461-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4115578-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4105762-A | Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlling phytopathogenic fungi using them | ROHM AND HAAS COMPANY (US) | 1978-08-08 | — | — | US | disclosed |