Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | GAA | P10253 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11809179 | 0.98 | L3MBTL1 (0.50) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL11807577 | 0.82 | L3MBTL1 (0.53) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL9428983 | 0.81 | L3MBTL1 (0.51) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL12462878 | 0.79 | L3MBTL1 (0.66) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL12463182 | 0.79 | L3MBTL1 (0.66) | L3MBTL1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL28713817 | 0.70 | NOX1 (0.81) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL8988 | 0.68 | L3MBTL1 (1.00) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL2423882 | 0.68 | L3MBTL1 (0.61) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL9171801 | 0.68 | MAPT (0.54) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL9429121 | 0.68 | GAA (0.50) | L3MBTL1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948889-A | CHEMICAL INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1976-04-06 | — | — | US | claimed |
| US-4232027-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-3948889-A | CHEMICAL INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1976-04-06 | — | — | US | disclosed |