Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807577 | 0.84 | L3MBTL1 (0.53) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL5020109 | 0.81 | MEN1 (0.49) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL7430660 | 0.75 | MEN1 (0.52) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL5746504 | 0.73 | NPC1 (0.69) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL5746497 | 0.73 | NPC1 (0.69) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL10352645 | 0.73 | L3MBTL1 (0.58) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL10772188 | 0.73 | GAA (0.44) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL3176131 | 0.72 | NOX1 (0.68) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL12463182 | 0.72 | L3MBTL1 (0.66) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL12462878 | 0.72 | L3MBTL1 (0.66) | MAPTGAAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430012-B1 | Process for preparing 2-Aromatic-3-halobenzothiazepines | MARION MERRELL DOW INC (US) | 1995-05-10 | — | — | EP | claimed |
| EP-0430012-A2 | Process for preparing 2-Aromatic-3-halobenzothiazepines | MARION MERRELL DOW INC. (US) | 1991-06-05 | — | — | EP | claimed |
| US-4983733-A | Process for preparing 2-aromatic-3-halobenzothiazepines | MARION LABORATORIES, INC. (US) | 1991-01-08 | — | — | US | claimed |
| EP-0430012-B1 | Process for preparing 2-Aromatic-3-halobenzothiazepines | MARION MERRELL DOW INC (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0430012-A2 | Process for preparing 2-Aromatic-3-halobenzothiazepines | MARION MERRELL DOW INC. (US) | 1991-06-05 | — | — | EP | disclosed |
| EP-0430012-A2 | Process for preparing 2-Aromatic-3-halobenzothiazepines | MARION MERRELL DOW INC. (US) | 1991-06-05 | — | — | EP | disclosed |
| US-4983733-A | Process for preparing 2-aromatic-3-halobenzothiazepines | MARION LABORATORIES, INC. (US) | 1991-01-08 | — | — | US | disclosed |
| US-4983733-A | Process for preparing 2-aromatic-3-halobenzothiazepines | MARION LABORATORIES, INC. (US) | 1991-01-08 | — | — | US | disclosed |