SCHEMBL1145282

SCHEMBL1145282

O=C(O)C(=Cc1ccccc1)CCOc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.53
CYP2C9 P11712 2/20 0.53
ALOX5 P09917 2/20 0.50
PTGES O14684 1/20 0.50
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
RAB9A P51151 1/20 0.47
RECQL P46063 2/20 0.46
TSHR P16473 1/20 0.46
PKM P14618 1/20 0.46
HDAC1 Q13547 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014099 0.83 CYP3A4 (0.56) CYP3A4CYP2C9SMN1; SMN2RECQLKDM4E
SCHEMBL372386 0.83 CYP1A2 (0.51) CYP3A4CYP2C9CYP1A2CYP2C19SMN1; SMN2
SCHEMBL11162670 0.79 CYP3A4 (0.51) CYP3A4CYP2C9ALOX5PTGESPPARG
SCHEMBL688557 0.79 CYP3A4 (0.51) CYP3A4CYP2C9ALOX5PTGESPPARG
SCHEMBL11312429 0.78 CYP3A4 (0.50) CYP3A4CYP2C9ALOX5PTGESPPARG
SCHEMBL5698377 0.77 CYP3A4 (0.61) CYP3A4CYP2C9SMN1; SMN2RAB9ARECQL
SCHEMBL3793616 0.77 CYP3A4 (0.61) CYP3A4CYP2C9CYP2C19RECQLTSHR
SCHEMBL7699017 0.76 USP2 (0.44) CYP3A4CYP2C9ALOX5PTGESPPARG
SCHEMBL27812598 0.76 CYP3A4 (0.56) CYP3A4CYP2C9ALOX5PTGESPPARG
SCHEMBL27812605 0.76 CYP3A4 (0.56) CYP3A4CYP2C9ALOX5PTGESPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110028641-A1 Radiation Curable Compositions CYTEC SURFACE SPECIALTIES, S.A. (BE) 2011-02-03 US disclosed