Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791590 | 0.77 | USP2 (0.57) | USP2GAAMAPTKDM4EMEN1 | |
| SCHEMBL1145282 | 0.76 | CYP3A4 (0.53) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL10788826 | 0.73 | MEN1 (0.56) | USP2GAAMAPTKDM4EMEN1 | |
| SCHEMBL2994100 | 0.72 | AKR1C3 (0.39) | USP2GAAMAPTKDM4EMEN1 | |
| SCHEMBL1469995 | 0.71 | KDM4E (0.53) | USP2GAAMAPTKDM4EMEN1 | |
| SCHEMBL1470608 | 0.71 | KDM4E (0.53) | USP2GAAMAPTKDM4EMEN1 | |
| SCHEMBL6915210 | 0.70 | CYP3A4 (0.47) | MAPTMEN1TP53KMT2ACYP3A4 | |
| SCHEMBL8421296 | 0.70 | CHRNA7 (0.49) | USP2GAAMAPTKDM4EMEN1 | |
| SCHEMBL8421295 | 0.70 | CHRNA7 (0.49) | USP2GAAMAPTKDM4EMEN1 | |
| SCHEMBL8099817 | 0.70 | GAA (0.74) | USP2GAAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350845-B1 | POLYAMIDEIMIDE COPOLYMERS FOR NONABSORBENT HEAT RESISTANT COMPOSITIONS | KANEKA CORPORATION (JP) | 2002-02-26 | — | — | US | disclosed |