Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23069368 | 0.85 | KDM4E (0.47) | ALOX5PTGESPPARGAKR1C3LMNA | |
| SCHEMBL490257 | 0.85 | KDM4E (0.47) | ALOX5PTGESPPARGAKR1C3LMNA | |
| SCHEMBL6144649 | 0.83 | CYP3A4 (0.54) | CYP3A4CYP2C9MEN1KMT2ARECQL | |
| SCHEMBL3256825 | 0.81 | CYP3A4 (0.59) | CYP3A4CYP2C9MEN1KMT2ARECQL | |
| SCHEMBL8858244 | 0.81 | CYP3A4 (0.59) | CYP3A4CYP2C9MEN1KMT2ARECQL | |
| SCHEMBL1145282 | 0.79 | CYP3A4 (0.53) | CYP3A4CYP2C9MEN1KMT2ARECQL | |
| SCHEMBL524131 | 0.78 | ALOX5 (0.59) | CYP3A4CYP2C9MEN1KMT2ARECQL | |
| SCHEMBL1786246 | 0.78 | ALOX5 (0.59) | CYP3A4CYP2C9MEN1KMT2ARECQL | |
| SCHEMBL8702152 | 0.78 | ALOX5 (0.59) | CYP3A4CYP2C9MEN1KMT2ARECQL | |
| SCHEMBL524132 | 0.78 | ALOX5 (0.59) | CYP3A4CYP2C9MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1793792-B1 | COMPOSITION COMPRISING THE EXTRACT OF ACTINIDIA ARGUTA FOR PREVENTING AND TREATING ALOPECIA AND SEBORRHEIC SKIN DISORDERS | HELIXIR CO LTD (KR) | 2012-02-29 | — | — | EP | disclosed |
| EP-2329835-A1 | Composition comprising the extract of actinidia arguta and related species for the prevention and treatment of allergic disease and non-allergic inflammatory disease | Helixir Co., Ltd. (KR) | 2011-06-08 | — | — | EP | disclosed |
| US-7932232-B2 | Inhibits activity of tyrosinase | BIOLAND LTD. (KR) | 2011-04-26 | — | — | US | disclosed |