Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457836 | 0.86 | — | — | |
| SCHEMBL11466731 | 0.84 | ALDH1A1 (0.39) | TSHRALDH1A1CYP2C19MEN1GLA | |
| SCHEMBL946713 | 0.83 | TSHR (0.39) | TSHRALDH1A1CYP2C19MEN1GLA | |
| SCHEMBL8019833 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL8009891 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL11128886 | 0.77 | CA12 (0.50) | TSHRALDH1A1CYP2C19MEN1GLA | |
| SCHEMBL11471995 | 0.76 | — | — | |
| SCHEMBL11464256 | 0.76 | ALDH1A1 (0.39) | TSHRALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL10045110 | 0.75 | CYP2C19 (0.48) | TSHRALDH1A1CYP2C19MEN1GLA | |
| SCHEMBL8989707 | 0.75 | TDP1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223138-A | VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |