Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9137032 | 0.97 | TDP1 (0.53) | TDP1 | |
| Diethanolamine SCHEMBL7608596 | 0.82 | TDP1 (0.62) | TDP1ROCK2 | |
| SCHEMBL9312999 | 0.79 | TDP1 (0.43) | TDP1 | |
| SCHEMBL11466731 | 0.79 | ALDH1A1 (0.39) | TDP1 | |
| SCHEMBL2423730 | 0.78 | TDP1 (0.77) | TDP1ROCK2 | |
| SCHEMBL2058467 | 0.78 | TDP1 (0.77) | TDP1ROCK2 | |
| Hydrochloric Acid SCHEMBL4515521 | 0.77 | TDP1 (0.48) | TDP1ROCK2 | |
| SCHEMBL18863093 | 0.77 | TDP1 (0.37) | TDP1 | |
| SCHEMBL2058471 | 0.76 | TDP1 (0.71) | TDP1ROCK2BLM | |
| SCHEMBL5170349 | 0.76 | TDP1 (0.71) | TDP1ROCK2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600370-B1 | Di-(3-(2-chloroethylsulphonyl)-1-propylamine hydrochloride and method for its preparation | HOECHST AG (DE) | 1996-07-17 | — | — | EP | claimed |
| US-5446201-A | Di(3-(2-chloroethylsulfonyl)-1-propyl)amine hydrochloride and a process for its preparation | HOECHST AG (DE) | 1995-08-29 | — | — | US | claimed |
| EP-0600370-A1 | Di-(3-(2-chloroethylsulphonyl)-1-propylamine hydrochloride and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | claimed |
| EP-0600370-B1 | Di-(3-(2-chloroethylsulphonyl)-1-propylamine hydrochloride and method for its preparation | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5446201-A | Di(3-(2-chloroethylsulfonyl)-1-propyl)amine hydrochloride and a process for its preparation | HOECHST AG (DE) | 1995-08-29 | — | — | US | disclosed |
| US-5446201-A | Di(3-(2-chloroethylsulfonyl)-1-propyl)amine hydrochloride and a process for its preparation | HOECHST AG (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0600370-A1 | Di-(3-(2-chloroethylsulphonyl)-1-propylamine hydrochloride and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0600370-A1 | Di-(3-(2-chloroethylsulphonyl)-1-propylamine hydrochloride and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |