Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.30 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1591295 | 0.80 | TDP1 (0.43) | SLC22A6TDP1CYP2C19SMN1; SMN2CYP2D6 | |
| SCHEMBL17307614 | 0.78 | TDP1 (0.42) | SLC22A6TDP1CYP2C19SMN1; SMN2ALOX15 | |
| SCHEMBL17426712 | 0.78 | TDP1 (0.42) | SLC22A6TDP1CYP2C19SMN1; SMN2ALOX15 | |
| SCHEMBL1318048 | 0.75 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL27548783 | 0.74 | KMT2A (0.36) | SMN1; SMN2ALOX15CYP2D6LMNA | |
| SCHEMBL17956705 | 0.70 | NAALAD2 (0.37) | SLC22A6TDP1TSHRHIF1ALMNA | |
| SCHEMBL28533323 | 0.70 | GPR84 (0.33) | SLC22A6TDP1ADRA1A | |
| SCHEMBL12189688 | 0.70 | SLC22A6 (0.31) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL14261039 | 0.70 | SLC22A6 (0.35) | SLC22A6TDP1CYP2C19SMN1; SMN2ALOX15 | |
| SCHEMBL21273015 | 0.68 | SLC22A6 (0.33) | SLC22A6TDP1SMN1; SMN2ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206120-A | Oxaazabicycloheptane antibiotics | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |