Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454377 | 1.00 | POLB (0.33) | POLBKMT2A | |
| SCHEMBL11454376 | 1.00 | POLB (0.33) | POLBKMT2A | |
| SCHEMBL7433974 | 0.80 | POLB (0.35) | POLBKMT2A | |
| SCHEMBL7362669 | 0.72 | POLB (0.32) | POLB | |
| SCHEMBL7362671 | 0.72 | POLB (0.32) | POLB | |
| SCHEMBL6431140 | 0.72 | POLB (0.32) | POLB | |
| SCHEMBL11253207 | 0.66 | RGS12 (0.30) | — | |
| SCHEMBL11198292 | 0.65 | ALDH1A1 (0.31) | POLB | |
| SCHEMBL11245438 | 0.63 | TP53 (0.34) | — | |
| SCHEMBL1568140 | 0.61 | POLB (0.42) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |