SCHEMBL1145463

SCHEMBL1145463

NCc1ccc(F)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29726521 1.00
Hydrochloric Acid SCHEMBL5009749 0.98 LOXL2 (0.47)
SCHEMBL12496644 0.83 HRH3 (0.56)
SCHEMBL3635565 0.82 TAAR1 (0.52)
SCHEMBL23124232 0.79 CYP2A6 (0.48)
SCHEMBL29745082 0.79 CYP2A6 (0.48)
SCHEMBL771164 0.78
SCHEMBL344739 0.76
SCHEMBL3995156 0.76
SCHEMBL1273680 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116528599-B Multi-tooth ligand modified perovskite solar cell and preparation method thereof 长江三峡集团实业发展(北京)有限公司 2025-01-24 CN claimed
CN-116528599-A Multi-tooth ligand modified perovskite solar cell and preparation method thereof 长江三峡集团实业发展(北京)有限公司 2023-08-01 CN claimed
CN-1286813-C Cyanoacrylate compounds containing fluoro pyridine-methylamino group and their bioactivity UNIV NANKAI (CN) 2006-11-29 CN claimed
CN-1594294-A Cyanoacrylate compounds containing fluoro pyridine-methylamino group and their bioactivity UNIV NANKAI (CN) 2005-03-16 CN claimed
EP-4308125-B1 PLASMA KALLIKREIN INHIBITORS MERCK SHARP & DOHME LLC (US) 2026-04-22 EP disclosed
US-20250179072-A1 TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2025-06-05 US disclosed
CN-116528599-B Multi-tooth ligand modified perovskite solar cell and preparation method thereof 长江三峡集团实业发展(北京)有限公司 2025-01-24 CN disclosed
US-20240262827-A1 TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2024-08-08 US disclosed
US-20240190892-A1 PLASMA KALLIKREIN INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-06-13 US disclosed
US-11970497-B2 Tricyclic AKR1C3 dependent KARS inhibitors NOVARTIS AG (CH) 2024-04-30 US disclosed
EP-4349839-A2 TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS Novartis AG (CH) 2024-04-10 EP disclosed
EP-4308125-A1 PLASMA KALLIKREIN INHIBITORS Merck Sharp & Dohme LLC (US) 2024-01-24 EP disclosed
WO-2006083673-A2 PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES ABBOTT LABORATORIES (US) 2006-08-10 WO disclosed
US-20060173050-A1 Inhibitors of c-Jun N-terminal kinases ABBVIE INC. 2006-08-03 US disclosed
EP-1598349-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-11-23 EP disclosed
US-20050101783-A1 N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide KUREHA CORPORATION (JP) 2005-05-12 US disclosed
CN-1594294-A Cyanoacrylate compounds containing fluoro pyridine-methylamino group and their bioactivity UNIV NANKAI (CN) 2005-03-16 CN disclosed
EP-1391450-A1 N-(HETEROCYCLE-METHYL)ALKYLAMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND BACTERICIDE Kureha Chemical Industry Co., Ltd. (JP) 2004-02-25 EP disclosed
US-6271385-B1 FUNGICIDES (SUCH AS THOSE FOR USE IN FARMING AND HORTICULTURE). KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-08-07 US disclosed
EP-1020441-A1 N-HETEROCYCLIC METHYLPROPYLAMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND GERMICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed