SCHEMBL114551

SCHEMBL114551

O=C(O)Cc1[nH]c2ccccc2c1O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.54
KDM4E B2RXH2 8/20 0.54
MAPT P10636 5/20 0.54
GAA P10253 2/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
EGFR P00533 2/20 0.53
IDE P14735 1/20 0.50
MPI P34949 1/20 0.50
CACNA1B Q00975 1/20 0.50
APBA1 Q02410 1/20 0.50
HPGD P15428 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30479099 1.00 ALDH1A1 (0.54) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL8064218 0.81 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL5499463 0.81 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL9250840 0.81 KDM4E (0.53) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL11187489 0.81 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL9457713 0.80 KDM4E (0.53) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL10685190 0.79 KDM4E (0.64) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL6702846 0.78 KDM4E (0.68) ALDH1A1KDM4EMAPTGAAIDE
SCHEMBL2648556 0.78 AHR (0.55) ALDH1A1KDM4EMAPTGAACASP1
SCHEMBL28516422 0.77 KDM4E (0.66) ALDH1A1KDM4EMAPTGAACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122084713-A Microelectrode, probe and electrochemical detection device 2026-05-26 CN claimed
WO-2025068213-A1 USE OF A MARKER SET FOR DETERMINING THE RISK OF HAVING OR DEVELOPING BLADDER CANCER NUMARES AG (DE) 2025-04-03 WO claimed
CN-117990671-A Eu (Eu)3+Application of complex in fluorescence detection of hydroxy indoleacetic acid 广州大学 2024-05-07 CN claimed
EP-3522172-B1 METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT CHILDRENS HOSPITAL MED CT (US) 2021-10-20 EP claimed
EP-3522172-A1 METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT Cincinnati Children's Hospital Medical Center (US) 2019-08-07 EP claimed
US-20190131015-A1 COMPUTER IMPLEMENTED SYSTEM AND METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT CHILDREN'S HOSPITAL MEDICAL CENTER 2019-05-02 US claimed
EP-2425356-B1 COMPUTER IMPLEMENTED SYSTEM AND METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT CINCINNATI CHILDRENS HOSPITAL MEDICAL CENTER (US) 2019-03-13 EP claimed
US-10204707-B2 Computer implemented system and method for assessing a neuropsychiatric condition of a human subject CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2019-02-12 US claimed
EP-2425356-A1 COMPUTER IMPLEMENTED SYSTEM AND METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT Cincinnati Children's Hospital Medical Center (US) 2012-03-07 EP claimed
US-20120041911-A1 COMPUTER IMPLEMENTED SYSTEM AND METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2012-02-16 US claimed
WO-2011138142-A1 COMPOSITIONS AND USE OF SULFASALAZINE ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2011-11-10 WO claimed
WO-2010126867-A1 COMPUTER IMPLEMENTED SYSTEM AND METHOD FOR ASSESSING A NEUROPSYCHIATRIC CONDITION OF A HUMAN SUBJECT CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2010-11-04 WO claimed
CN-122084713-A Microelectrode, probe and electrochemical detection device 2026-05-26 CN disclosed
US-20250377363-A1 METHODS RELATING TO DIAGNOSING STABILITY FOLLOWING RENAL TRANSPLANTATION THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-12-11 US disclosed
US-20250228842-A1 USES OF A SOMATOSTATIN MODULATOR FOR THE TREATMENT OF CARCINOID SYNDROME Crinetics Pharmaceuticals, Inc. 2025-07-17 US disclosed
US-12329726-B2 Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-06-17 US disclosed
WO-1993004373-A1 CALCIUM RECEPTOR ACTIVE MOLECULES NPS PHARMACEUTICALS, INC. (US) 1993-03-04 WO disclosed
EP-0284725-A2 Indoxyl-beta-d-glucuronide and method for making QUEEN'S UNIVERSITY AT KINGSTON (CA) 1988-10-05 EP disclosed
US-4083982-A 3-(PARA-TRIFLUOROMETHYLPHENOXY)-N-METHYL-3-PHENYL-PROPYLAMINE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1978-04-11 US disclosed
US-4035511-A 3-(P-TRIFLUOROMETHYLPHENOXY)-N-METHYL-3-PHENYLPROPYLAMINE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1977-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228842-A1 USES OF A SOMATOSTATIN MODULATOR FOR THE TREATMENT OF CARCINOID SYNDROME SSTR4, SSTR5, SSTR2 ALDH1A1 3940/4885KDM4E 2881/4885MAPT 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.