Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332136 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL28900980 | 0.83 | KMT2A (0.61) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL28819186 | 0.82 | MAPT (0.46) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL10685190 | 0.81 | KDM4E (0.64) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL28819201 | 0.81 | KDM4E (0.58) | ALDH1A1MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL28472093 | 0.81 | OXER1 (0.61) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL114551 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL30479099 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL28468727 | 0.80 | OXER1 (0.63) | ALDH1A1MAPTKDM4EGAACASP1 | |
| SCHEMBL28819182 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967484-B1 | METHODS FOR DETECTING OR ASSAYING VIRUS | ADVANCED LIFE SCIENCE INST INC (JP) | 2007-05-02 | — | — | EP | claimed |
| CN-105308024-A | Bicyclic nitrogen-containing aromatic heterocyclic amide compound | ASTELLAS PHARMA INC | 2016-02-03 | — | — | CN | disclosed |
| WO-2000064917-A2 | SYNTHETIC INDOLOCARBAZOLE REGIOISOMERS AND USES THEREOF | ADVANCED LIFE SCIENCES INC. (US) | 2000-11-02 | — | — | WO | disclosed |
| US-4808728-A | Production of indolepyruvic acid and the 5-hydroxy derivative thereof | POLIFARMA S.P.A. (IT) | 1989-02-28 | — | — | US | disclosed |