Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005754 | 0.79 | NPC1 (0.67) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| SCHEMBL14584377 | 0.78 | HSD17B10 (0.75) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| SCHEMBL11174292 | 0.76 | NPC1 (0.58) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| SCHEMBL5550842 | 0.76 | NPC1 (0.58) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| SCHEMBL2705561 | 0.74 | NFKB1 (0.61) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| SCHEMBL209971 | 0.73 | NFKB1 (0.59) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| SCHEMBL208477 | 0.72 | NPC1 (0.53) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| Lithium Ion SCHEMBL209972 | 0.72 | NPC1 (0.53) | TP53MAPTNFKB1RAB9ASMN1; SMN2 | |
| SCHEMBL13665379 | 0.72 | GAA (0.37) | TP53MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11462094 | 0.70 | RAB9A (0.51) | TP53MAPTNFKB1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222946-A | ANTIALLERGEN, HYPERSENSITIVITY | LILLY INDUSTRIES, LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| US-4187232-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1980-02-05 | — | — | US | disclosed |