Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 10/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11447977 | 0.96 | GHSR (0.53) | GHSRSLC6A2SLC6A4SLC6A3SLC6A9 | |
| SCHEMBL11466657 | 0.85 | POLB (0.43) | SLC6A2SLC6A4SLC6A3POLBCACNA2D1 | |
| SCHEMBL11466701 | 0.85 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3POLBCACNA2D1 | |
| SCHEMBL11467500 | 0.85 | CHRNB4 (0.53) | SLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL11449222 | 0.85 | POLB (0.43) | SLC6A2SLC6A4SLC6A3POLBCACNA2D1 | |
| SCHEMBL11458218 | 0.85 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL11448946 | 0.83 | LTA4H (0.51) | GHSRPOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL11447773 | 0.82 | LTA4H (0.51) | GHSRSLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL11448415 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3POLBCACNA2D1 | |
| SCHEMBL11456286 | 0.82 | POLB (0.41) | SLC6A2SLC6A4POLBCACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |