⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145673 | 1.00 | CXCR3 (0.42) | — | |
| SCHEMBL11065315 | 1.00 | CXCR3 (0.42) | — | |
| SCHEMBL10882411 | 1.00 | CXCR3 (0.42) | — | |
| SCHEMBL316975 | 0.97 | — | — | |
| SCHEMBL880190 | 0.90 | — | — | |
| Alcohol SCHEMBL10859711 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL11316288 | 0.81 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL11316294 | 0.81 | SMN1; SMN2 (0.46) | — | |
| Cyclopentene SCHEMBL17472538 | 0.81 | ALDH1A1 (0.32) | — | |
| SCHEMBL10877304 | 0.81 | SMN1; SMN2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128575-A1 | Traction fluid composition | GEIGER RENE | 2006-06-15 | — | — | US | claimed |
| WO-2004061057-A1 | TRACTION FLUID COMPOSITION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-22 | — | — | WO | claimed |
| US-7888374-B2 | Inhibitors of c-jun N-terminal kinases | ABBOTT LABORATORIES (US) | 2011-02-15 | — | — | US | disclosed |
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | ABBVIE INC. | 2006-08-03 | — | — | US | disclosed |
| US-20060128575-A1 | Traction fluid composition | GEIGER RENE | 2006-06-15 | — | — | US | disclosed |
| US-20050171132-A1 | Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists | XIN ZHILI (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
| WO-2004061057-A1 | TRACTION FLUID COMPOSITION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| CN-1151144-C | Benzopyrans and benzothiopyrans as RAR selective retinoid agonists | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1370156-A | Benzopyrans and benzothiopyrans as RAR selective retinoid agonists | HOFFMANN LA ROCHE (CH) | 2002-09-18 | — | — | CN | disclosed |