⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23880732 | 0.80 | — | — | |
| SCHEMBL130382 | 0.80 | — | — | |
| SCHEMBL13044910 | 0.76 | PSMD14 (0.34) | — | |
| SCHEMBL60953 | 0.72 | — | — | |
| SCHEMBL29649153 | 0.72 | — | — | |
| SCHEMBL30548743 | 0.72 | — | — | |
| SCHEMBL8747477 | 0.72 | CYP2A6 (0.43) | — | |
| SCHEMBL467333 | 0.72 | — | — | |
| SCHEMBL21520 | 0.72 | — | — | |
| SCHEMBL5132326 | 0.72 | CES2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290911-A | Forming polymers by catalytic oxidative coupling | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1994-03-01 | — | — | US | claimed |
| WO-2021147974-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS AURORA A SELECTIVE INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-07-29 | — | — | WO | disclosed |
| EP-3587406-B1 | 2-HYDROXY-1-{4-[(4-PHENYLPHENYL)CARBONYL]PIPERAZIN-1-YL}ETHAN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS FOR THE TREATMENT OF CANCER | FORMA THERAPEUTICS INC (US) | 2021-01-27 | — | — | EP | disclosed |
| CN-110372550-A | Aryl ether and application thereof | 佩洛通治疗公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105530923-B | Aryl ethers and their use | 佩洛通治疗公司 | 2019-07-23 | — | — | CN | disclosed |
| US-9783736-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| EP-2606031-B1 | AUTOTAXIN INHIBITORS AND USES THEREOF | AMIRA PHARMACEUTICALS INC (US) | 2017-09-27 | — | — | EP | disclosed |
| CN-105530923-A | Aryl ethers and their use | PELOTON THERAPEUTICS INC | 2016-04-27 | — | — | CN | disclosed |
| CN-103228625-B | 4-substituted-3-phenylsulfanylmethyl-bicyclo[3.1.0]hexane compounds as mGluR 2/3 antagonists | LILLY CO ELI | 2014-12-03 | — | — | CN | disclosed |
| CN-103228625-A | 4-substituted-3-phenylsulfanylmethyl-bicyclo[3.1.0]hexane compounds as mGluR 2/3 antagonists | LILLY CO ELI | 2013-07-31 | — | — | CN | disclosed |
| CN-1646142-A | Method of treating cardiac arrhythmias comprising administration of an A1 adenosine agonist in combination with a beta blocker, calcium channel blocker, or cardiac glycoside | CV THERAPEUTICS INC (US) | 2005-07-27 | — | — | CN | disclosed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
| EP-0402481-B1 | PRODUCTION OF POLYARYLENE THIOETHER | PROD DEV RES INST (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5290911-A | Forming polymers by catalytic oxidative coupling | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5153305-A | From diaryl disulfide; mild conditions using organometallic catalyst | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1992-10-06 | — | — | US | disclosed |
| US-4983720-A | Process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0402481-A1 | PRODUCTION OF POLYARYLENE THIOETHER | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1990-12-19 | — | — | EP | disclosed |
| US-4931542-A | Process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0281036-A2 | A process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |