Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331790 | 0.95 | ALDH1A1 (0.47) | LMNAALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL11447557 | 0.83 | OPRM1 (0.50) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL11446647 | 0.81 | TP53 (0.48) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL11446684 | 0.80 | ALDH1A1 (0.51) | LMNAALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL11448317 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL11446669 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL11341610 | 0.79 | KDM4E (0.50) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL11446503 | 0.79 | ALDH1A1 (0.47) | LMNAALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL6601536 | 0.78 | KDM4E (0.64) | LMNAALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL11446586 | 0.78 | ALDH1A1 (0.40) | LMNAALDH1A1KDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4157398-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4156733-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |